Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.35 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979137 | 0.93 | FFAR1 (0.41) | CYP2A6ACACBEGLN1RETFFAR1 | |
| SCHEMBL8979153 | 0.93 | FFAR1 (0.41) | CYP2A6ACACBEGLN1RETFFAR1 | |
| SCHEMBL8979129 | 0.92 | CYP2A6 (0.59) | CYP2A6ACACBFFAR1TP53 | |
| SCHEMBL8978971 | 0.92 | ACACB (0.40) | CYP2A6ACACBTAAR1FFAR1FFAR4 | |
| SCHEMBL8978833 | 0.92 | ACACB (0.40) | CYP2A6ACACBTAAR1FFAR1FFAR4 | |
| SCHEMBL8979087 | 0.89 | PTPN11 (0.38) | CYP2A6TAAR1LMNAFFAR1FFAR4 | |
| SCHEMBL8978920 | 0.89 | PTPN11 (0.38) | CYP2A6TAAR1LMNAFFAR1FFAR4 | |
| SCHEMBL9293677 | 0.88 | CYP2A6 (0.53) | CYP2A6ACACBTAAR1LMNAEGLN1 | |
| SCHEMBL8755905 | 0.88 | CYP2A6 (0.40) | CYP2A6ACACBTAAR1LMNAEGLN1 | |
| SCHEMBL8978736 | 0.88 | HSD17B10 (0.43) | LMNAFFAR1FFAR4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| US-5356558-A | Compatibility, high speed response | SEIKO EPSON CORPORATION (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |