Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 12/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8978877 | 1.00 | FFAR1 (0.42) | FFAR1FFAR4ACACBPTPN11PTPRO | |
| SCHEMBL8979146 | 0.96 | FFAR1 (0.41) | FFAR1FFAR4ACACBTSHRHSD17B10 | |
| SCHEMBL8979100 | 0.96 | FFAR1 (0.41) | FFAR1FFAR4ACACBTSHRHSD17B10 | |
| SCHEMBL8979002 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR | |
| SCHEMBL8979013 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR | |
| SCHEMBL8978795 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR | |
| SCHEMBL8978729 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR | |
| SCHEMBL8979140 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR | |
| SCHEMBL8978885 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR | |
| SCHEMBL8978918 | 0.95 | HSD17B10 (0.43) | FFAR1FFAR4PTPN11PTPROTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0581272-B1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORP (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0581272-A1 | Tolane derivatives, liquid crystal compositions containing the derivatives and liquid crystal display device using the compositions | SEIKO EPSON CORPORATION (JP) | 1994-02-02 | — | — | EP | disclosed |