Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.83 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1343745 | 0.95 | MEN1 (0.75) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL3653375 | 0.95 | MEN1 (0.86) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL1341844 | 0.91 | MEN1 (1.00) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL1343741 | 0.86 | MEN1 (0.89) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL25555697 | 0.84 | MEN1 (0.86) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL20528149 | 0.82 | MEN1 (0.57) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL20528145 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1TSHRLMNA | |
| SCHEMBL15353029 | 0.79 | MEN1 (0.57) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL15353026 | 0.79 | MEN1 (0.57) | MEN1KMT2AALDH1A1TSHRCYP4F2 | |
| SCHEMBL11174634 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1TSHRCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552507-A | DI-(3-ISOCYANATOPROPYL) MALONIC ACID DIESTERS, MONOMERS FOR POLYURETHANES OR POLYUREAS THAT ARE PHOTOSTABLE AND WEATHER RESISTANT | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-03 | — | — | US | disclosed |