SCHEMBL8979306

SCHEMBL8979306

C=CCC(CC(=O)O)C(O)=S

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 2/20 0.42
GRIK2 Q13002 2/20 0.42
CPA1 P15085 3/20 0.41
FOLH1 Q04609 2/20 0.35
ABCC4 O15439 1/20 0.34
MAPT P10636 1/20 0.34
SLC22A6 Q4U2R8 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
CPB1 P15086 1/20 0.31
CPA3 P15088 1/20 0.31
CPB2 Q96IY4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7114024 0.82 GRIK1 (0.55) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL56402 0.82 GRIK1 (0.55) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL24215021 0.82 GRIK1 (0.55) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL8979302 0.82 GRIK1 (0.36) GRIK1GRIK2CPA1
SCHEMBL10524637 0.81 GRIK1 (0.41) GRIK1GRIK2CPA1CYP2C19
Hydrochloric Acid SCHEMBL531801 0.80 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL30502843 0.80 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
Methane SCHEMBL27860390 0.80 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL8972060 0.80 GRIK1 (0.53) GRIK1GRIK2CPA1FOLH1ABCC4
SCHEMBL531800 0.78 GRIK1 (0.42) GRIK1GRIK2CPA1FOLH1ABCC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5582760-A POLYOL ESTER BASED TURBINE OIL; OXIDATION AND CORROSION RESISTANCE, SILICON SEAL COMPATIBILITY EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-12-10 US claimed
CN-112351976-A Taxane-lipid-polysaccharide double-type couplet, preparation method and application thereof 圣多利康制药责任有限公司 2021-02-09 CN disclosed
CN-1805728-B Shampoo and body detergent composition TAKASAGO PERFUMERY CO LTD 2010-10-13 CN disclosed
CN-1306107-C Refining liquid for cotton fiber and conbinuous control method for cotton fiber enzyme rifining NEGASE GOSEI CO LTD (JP) 2007-03-21 CN disclosed
CN-1805728-A Shampoo and body detergent composition TAKASAGO PERFUMERY CO LTD (JP) 2006-07-19 CN disclosed
CN-1512003-A Refining liquid for cotton fiber and conbinuous control method for cotton fiber enzyme rifining 长�化成株式会社 2004-07-14 CN disclosed
CN-1318976-A Use of polymers as sticking agents RHODIA CHIMIE SA (FR) 2001-10-24 CN disclosed
US-5582760-A POLYOL ESTER BASED TURBINE OIL; OXIDATION AND CORROSION RESISTANCE, SILICON SEAL COMPATIBILITY EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-12-10 US disclosed
US-5582760-A POLYOL ESTER BASED TURBINE OIL; OXIDATION AND CORROSION RESISTANCE, SILICON SEAL COMPATIBILITY EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-12-10 US disclosed
US-5582760-A POLYOL ESTER BASED TURBINE OIL; OXIDATION AND CORROSION RESISTANCE, SILICON SEAL COMPATIBILITY EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-12-10 US disclosed
CN-1061151-A Cleaning compositions PROCTER & GAMBLE (US) 1992-05-20 CN disclosed
US-4670163-A HALOHYDROXYALKYLTHIO-SUBSTITUTED OR DIHYDROXYALKYLTHIO-SUBSTITUTED POLYCARBOXYLIC ACIDS AND SALTS PHILLIPS PETROLEUM COMPANY (US) 1987-06-02 US disclosed
US-4600519-A Process for improving friction modification properties of a power transmission fluid with an alkylthio succinic acid or anhydride EXXON RESEARCH & ENGINEERING CO. (US) 1986-07-15 US disclosed
US-4455429-A Oxazolines of 2-(alkylthio)succinic acids as an additive for drilling muds EXXON RESEARCH & ENGINEERING CO. (US) 1984-06-19 US disclosed
US-4431551-A OIL WELLS; METAL WORKING; LUBRICANTS; PHEOLOGY EXXON RESEARCH & ENGINEERING CO. (US) 1984-02-14 US disclosed
US-4422953-A SUBSTITUTED SUCCINIC ACIDS PETROLITE CORPORATION (US) 1983-12-27 US disclosed
US-4238575-A POLYALKYLTHIOETHYL METHACRYLATE, POLYOLEFINS CIBA-GEIGY CORPORATION (US) 1980-12-09 US disclosed
US-4152515-A PHOSPHOROUS-FREE LEVER BROTHERS COMPANY (US) 1979-05-01 US disclosed
US-4125516-A HEAT STABILIZER, ANTIOXIDANT, DISCOLORATION INHIBITON CIBA-GEIGY CORPORATION (US) 1978-11-14 US disclosed