Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979387 | 0.78 | DHODH (0.43) | MMEDHODHMEN1KMT2AMAPT | |
| SCHEMBL8979383 | 0.73 | GAA (0.34) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3816789 | 0.69 | GAA (0.44) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3819630 | 0.67 | DHODH (0.48) | DHODHMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL263692 | 0.66 | GAA (0.41) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL13737931 | 0.66 | GAA (0.41) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL13738434 | 0.66 | GAA (0.41) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL21114440 | 0.64 | GAA (0.42) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL21114486 | 0.64 | GAA (0.42) | DHODHMEN1KMT2AALDH1A1GAA | |
| SCHEMBL21114439 | 0.64 | GAA (0.42) | DHODHMEN1KMT2AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322815-B1 | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO (JP) | 1996-05-15 | — | — | EP | disclosed |
| US-5312999-A | Propoxybenzene derivatives and process for preparing the same | DAIICHI SEIYAKU CO., LTD. (JP) | 1994-05-17 | — | — | US | disclosed |
| US-5136059-A | PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0322815-A2 | Propoxybenzene derivatives and process for preparing the same | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1989-07-05 | — | — | EP | disclosed |