SCHEMBL8979435

SCHEMBL8979435

C=CCOCC(O)CN[C@@H](C)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CYP2D6 P10635 3/20 0.43
ADRB2 P07550 8/20 0.42
ADRB1 P08588 8/20 0.42
LMNA P02545 2/20 0.42
CYP1A2 P05177 2/20 0.42
HTR1A P08908 2/20 0.42
SLC6A4 P31645 2/20 0.42
ADRA1A P35348 2/20 0.42
SLC22A1 O15245 1/20 0.42
HTR2A P28223 1/20 0.42
ADRB3 P13945 5/20 0.41
ADRA2C P18825 1/20 0.35
SLC6A2 P23975 1/20 0.35
BDKRB2 P30411 1/20 0.35
HTR2B P41595 1/20 0.35
KCNH2 Q12809 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979432 1.00 CA1 (0.46) CA1CA2CA7CYP2D6ADRB2
SCHEMBL15623789 0.86 CA1 (0.45) CA1CA2CA7CYP2D6ADRB2
SCHEMBL15602751 0.86 CA1 (0.45) CA1CA2CA7CYP2D6ADRB2
SCHEMBL11031043 0.85 CYP2D6 (0.45) CA1CA2CA7CYP2D6ADRB2
SCHEMBL11031040 0.85 CYP2D6 (0.45) CA1CA2CA7CYP2D6ADRB2
SCHEMBL15602747 0.80 CA1 (0.40) CA1CA2CA7CYP2D6ADRB2
SCHEMBL15680130 0.80 CA1 (0.40) CA1CA2CA7CYP2D6ADRB2
Urea SCHEMBL6903927 0.79 CA1 (0.44) CA1CA2CA7CYP2D6ADRB2
SCHEMBL11149710 0.79 CA1 (0.44) CA1CA2CA7CYP2D6ADRB2
SCHEMBL11149704 0.79 CA1 (0.44) CA1CA2CA7CYP2D6ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5576393-A NARROW PARTICLE SIZE DISTRIBUTION; EMULSION POLYMERIZATION RICOH COMPANY, LTD. (JP) 1996-11-19 US disclosed
US-5541031-A SPHERICAL PARTICLES WITH PROTRUSIONS ON SURFACE AND NARROW PARTICLE SIZE DISTRIBUTION RICOH COMPANY, LTD. (JP) 1996-07-30 US disclosed
EP-0324529-B1 Resinous microparticles useful in powdery toner for electrophotography NIPPON PAINT CO LTD (JP) 1996-05-15 EP disclosed
US-4968576-A POSITIVE CHARGING ABILITY, IMPROVED FLOWABILITY NIPPON PAINT CO., LTD. (JP) 1990-11-06 US disclosed
EP-0324529-A2 Resinous microparticles useful in powdery toner for electrophotography Nippon Paint Co., Ltd. (JP) 1989-07-19 EP disclosed
US-4468493-A High solid coating composition containing novel microparticles of crosslinked copolymer containing amphoionic groups NIPPON PAINT CO., LTD. (JP) 1984-08-28 US disclosed
US-4403065-A CARBOXY OR SULFONATE AMINE AND OTHER MONOMER NIPPON PAINT CO., LTD. (JP) 1983-09-06 US disclosed
US-4309327-A COATINGS, PIGMENT PASTES NIPPON PAINT CO., LTD. (JP) 1982-01-05 US disclosed