SCHEMBL8979726

SCHEMBL8979726

[CH2]c1c(F)c(F)c(OC(F)F)c(F)c1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8979731 0.74
SCHEMBL456535 0.69
SCHEMBL9562027 0.69
SCHEMBL8979598 0.69
SCHEMBL9561822 0.68 SLC6A2 (0.36)
SCHEMBL1073796 0.67 HSD17B10 (0.35)
SCHEMBL24460005 0.67
SCHEMBL43508 0.65 GRIN2D (0.32)
SCHEMBL24458162 0.62
SCHEMBL9785372 0.62 NQO1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0498724-B1 Esters of 3-(3,3,3-trifluoro-2-chloropropenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1996-05-15 EP claimed
JP-4352746-A None JP disclosed
US-5336670-A 2,2-dimethyl-3-(but-1-en-3-ynyl)-cyclopropane carboxylates ROUSSEL-UCLAF (FR) 1994-08-09 US disclosed
JP-H04352746-A NEW 3-(3,3,3-TRIFLUORO-2-CHLOROPROPENYL)-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC ACID ESTER, ITS PRODUCTION AND USE AS EXTERMINATOR FOR HARMFUL INSECT ROUSSEL UCLAF 1992-12-07 JP disclosed
US-4939172-A Novel cyclopropane carboxylates ROUSSEL UCLAF (FR) 1990-07-03 US disclosed