SCHEMBL8979993

SCHEMBL8979993

C=CCN1C(=O)CCC(C)(C)C1=O

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.42
GAA P10253 2/20 0.38
TSHR P16473 2/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
STS P08842 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
CYP19A1 P11511 1/20 0.33
CNR1 P21554 3/20 0.33
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
ALDH1A1 P00352 1/20 0.31
CASP3 P42574 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11936216 0.77 CHRM2 (0.44) TSHRMEN1KMT2AMAPTCYP19A1
SCHEMBL8295849 0.74 CYP19A1 (0.50) TSHRMEN1KMT2ACYP19A1
SCHEMBL288566 0.74 CYP3A4 (0.46) POLBGAATSHRL3MBTL1CYP3A4
SCHEMBL8903951 0.74 CYP3A4 (0.46) POLBGAATSHRL3MBTL1CYP3A4
SCHEMBL8282196 0.73 MEN1 (0.41) POLBGAATSHRMEN1KMT2A
SCHEMBL29044522 0.72 CYP3A4 (0.44) POLBGAATSHRL3MBTL1CYP3A4
SCHEMBL7287440 0.70 CYP3A4 (0.35) POLBGAAL3MBTL1CYP3A4ALDH1A1
SCHEMBL10953644 0.70 GAA (0.45) POLBGAATSHRMEN1KMT2A
SCHEMBL26361665 0.70 GAA (0.45) POLBGAATSHRMEN1KMT2A
SCHEMBL723082 0.70 POLB (0.43) POLBTSHRMEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449502-B1 Stabilization of methacrylic polymers against sterilizing radiation ROHM & HAAS (US) 1995-03-08 EP claimed
US-5276090-A Copolymers for blends with polyesters ROHM AND HAAS COMPANY (US) 1994-01-04 US claimed
US-5223578-A Thermoplastic ionomer ROHM AND HAAS COMPANY (US) 1993-06-29 US claimed
EP-0500314-A1 Process for preparing graft copolymers of polyglutarimides and aromatic polyesters ROHM AND HAAS COMPANY (US) 1992-08-26 EP claimed
EP-0404346-A1 Polyamide, polyglutarimide and impact modifier blends ROHM AND HAAS COMPANY (US) 1990-12-27 EP claimed
JP-4224802-A None JP disclosed
US-5585423-A POLYGLUTARIMIDE SHEETS, FILMS OR MOLDINGS CONTAINING HINDERED AMINE AND BENZOTRIAZOLE PHOTOSTABILIZERS ROHM AND HAAS COMPANY (US) 1996-12-17 US disclosed
JP-H04224802-A STABILIZATION OF METHACRYLIC POLYMERS AGAINST STERILIZING RADIATION ROHM & HAAS CO 1992-08-14 JP disclosed
EP-0404311-A1 Ultraviolet resistant glutarimide polymers ROHM AND HAAS COMPANY (US) 1990-12-27 EP disclosed
EP-0404346-A1 Polyamide, polyglutarimide and impact modifier blends ROHM AND HAAS COMPANY (US) 1990-12-27 EP disclosed