SCHEMBL8980263

SCHEMBL8980263

CC1CC/C(=C/c2ccc(Cl)cc2)C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.51
AKR1C1 Q04828 2/20 0.51
NPC1 O15118 4/20 0.48
RAB9A P51151 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 1/20 0.47
MAOB P27338 5/20 0.44
EGFR P00533 1/20 0.43
HPGD P15428 1/20 0.43
MITF O75030 1/20 0.43
HSP90AA1 P07900 1/20 0.43
CCR6 P51684 1/20 0.41
MEN1 O00255 1/20 0.41
LMNA P02545 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8154548 1.00 AKR1C3 (0.51) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL8674216 1.00 AKR1C3 (0.51) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL8882040 0.90 AKR1C3 (0.57) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL8852927 0.90 AKR1C3 (0.57) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL8145324 0.90 AKR1C3 (0.57) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL8883417 0.89 AKR1C3 (0.55) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL8883420 0.89 AKR1C3 (0.55) AKR1C3AKR1C1NPC1RAB9AKMT2A
SCHEMBL9048357 0.83 MAPT (0.61) NPC1RAB9AKMT2AMAPTSMN1; SMN2
SCHEMBL9047403 0.83 MAPT (0.61) NPC1RAB9AKMT2AMAPTSMN1; SMN2
SCHEMBL8675957 0.81 NPC1 (0.68) NPC1RAB9AKMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0712836-A1 Alkyl 3-benzylidene-1-alkyl-2-oxocyclopentanecarboxylate derivates as fungicides KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1996-05-22 EP disclosed
US-5519160-A FUNGICIDES KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1996-05-21 US disclosed
US-5380741-A Crop treatment method RHONE-POULENC AGROCHIMIE (FR) 1995-01-10 US disclosed
EP-0565463-A1 Triazol and imidazol-derivatives as fungicides RHONE-POULENC AGROCHIMIE (FR) 1993-10-13 EP disclosed