Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | CES1 | P23141 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.52 |
| ▸ | FEN1 | P39748 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methyl Alcohol SCHEMBL27972456 | 0.91 | MAPT (0.58) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| SCHEMBL45515 | 0.91 | MAPT (0.64) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| SCHEMBL10337516 | 0.91 | MAPT (0.64) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Water SCHEMBL18694848 | 0.89 | MAPT (0.61) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL194804 | 0.89 | MAPT (0.61) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Bromide SCHEMBL19378722 | 0.89 | MAPT (0.61) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL19378455 | 0.86 | MAPT (0.58) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Hydrochloric Acid SCHEMBL28205776 | 0.86 | MAPT (0.58) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Pivalate SCHEMBL28025123 | 0.83 | MAPT (0.50) | KMT2ACYP3A4MAPTTDP1MEN1 | |
| Sulfuric Acid SCHEMBL8748212 | 0.83 | MAPT (0.54) | KMT2ACYP3A4MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571822-A | AMINO-2-PHENYL-4-QUINOLONE DERIVATIVES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996010563-A1 | 2-ARYL-4-QUINOLONES AS ANTITUMOR COMPOUNDS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 1996-04-11 | — | — | WO | disclosed |