Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.54 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | TACR2 | P21452 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013472 | 1.00 | CDK1 (0.54) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL9013477 | 1.00 | CDK1 (0.54) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL8980803 | 1.00 | CDK1 (0.54) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL8980865 | 1.00 | CDK1 (0.54) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL8980871 | 1.00 | CDK1 (0.54) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL2278630 | 0.87 | CDK1 (0.55) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL19320477 | 0.87 | CDK1 (0.55) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL6689618 | 0.87 | CDK1 (0.55) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL6689622 | 0.87 | CDK1 (0.55) | CDK1KAT8PPARAPTGS2ESR1 | |
| SCHEMBL510844 | 0.87 | CDK1 (0.55) | CDK1KAT8PPARAPTGS2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743937-A1 | BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF | HENKEL CORPORATION (US) | 1996-11-27 | — | — | EP | claimed |
| WO-1995021152-A1 | BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF | HENKEL CORPORATION (US) | 1995-08-10 | — | — | WO | claimed |
| EP-0743937-A1 | BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF | HENKEL CORPORATION (US) | 1996-11-27 | — | — | EP | disclosed |
| US-5514823-A | Bis-(alkylsalicylidene)ethylene or phenylene diamines and transition metal complexes thereof | HENKEL CORPORATION (US) | 1996-05-07 | — | — | US | disclosed |
| WO-1995021152-A1 | BIS-(ALKYLSALICYLIDENE)ETHYLENE OR PHENYLENE DIAMINES AND TRANSITION METAL COMPLEXES THEREOF | HENKEL CORPORATION (US) | 1995-08-10 | — | — | WO | disclosed |