SCHEMBL8982008

SCHEMBL8982008

[CH2]C(Cl)CCCCCCCCCCCCCCCCCCCCCC

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.44
THRB P10828 1/20 0.44
LMNA P02545 1/20 0.44
DNM1 Q05193 2/20 0.43
OPRM1 P35372 1/20 0.42
ALDH1A1 P00352 1/20 0.41
GPR84 Q9NQS5 3/20 0.39
FDPS P14324 3/20 0.39
SPHK1 Q9NYA1 1/20 0.39
FFAR1 O14842 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL237153 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL7863914 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL7869268 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL9427759 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL9510813 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL9428891 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL8638564 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL4312065 1.00
SCHEMBL7866734 1.00 TSHR (0.44) TSHRTHRBLMNADNM1OPRM1
SCHEMBL8083117 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5498477-A N-phenylhydroxylamine polymers, and associated methods of preparation and use NESTE OY (FI) 1996-03-12 US disclosed
US-5478862-A Having progestational activity with minimum ancillary hormonal activity; antiovulation agents SRI INTERNATIONAL (US) 1995-12-26 US disclosed
EP-0500899-B1 NOVEL 15,16-SECO-19-NOR PROGESTINS STANFORD RES INST INT (US) 1995-10-18 EP disclosed
US-5321044-A Ovulation suppression SRI INTERNATIONAL (US) 1994-06-14 US disclosed
US-5312897-A N-phenylhydroxylamine polymer, method of preparation NESTE OY (FI) 1994-05-17 US disclosed
WO-1994004595-A1 N-PHENYLHYDROXYLAMINE POLYMERS, AND ASSOCIATED METHODS OF PREPARATION AND USE NESTE OY (FI) 1994-03-03 WO disclosed
EP-0500899-A1 NOVEL 15,16-SECO-19-NOR PROGESTINS. STANFORD RES INST INT (US) 1992-09-02 EP disclosed
US-5116830-A Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses SRI INTERNATIONAL (US) 1992-05-26 US disclosed
US-5116865-A Antifertility Agents SRI INTERNATIONAL, A CORP OF CA 1992-05-26 US disclosed
WO-1992004309-A1 NOVEL 15,16-SECO-19-NOR PROGESTINS SRI INTERNATIONAL (US) 1992-03-19 WO disclosed
EP-0190149-B1 STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF SRI INTERNATIONAL (US) 1989-12-13 EP disclosed
US-4788218-A MALE FERTILITY CONTROL SRI INTERNATIONAL (US) 1988-11-29 US disclosed
EP-0190149-A1 STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF. STANFORD RES INST INT (US) 1986-08-13 EP disclosed
EP-0182808-A1 17 a?$g(b)-HYDROXY-7$g(a)-METHYL-D-HOMO-19-NORANDROST-4,16-DIENE-3-ONE AND THE 17-ESTERS THEREOF: METHODS OF PREPARATION AND USES SRI INTERNATIONAL (US) 1986-06-04 EP disclosed
WO-1986001208-A1 STEREOISOMETRICALLY PURE 17-ALPHA-ETHYNYL-ESTRA-2-EN-17BETA-OL AND ESTERS THEREOF SRI INTERNATIONAL (US) 1986-02-27 WO disclosed
WO-1985005361-A1 17abeta-HYDROXY-7alpha-METHYL-D-HOMO-19-NORANDROST-4,16-DIENE-3-ONE AND THE 17-ESTERS THEREOF: METHODS OF PREPARATION AND USES SRI INTERNATIONAL (US) 1985-12-05 WO disclosed