Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.70 |
| ▸ | RAB9A | P51151 | 4/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.70 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | USP2 | O75604 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | RARB | P10826 | 6/20 | 0.69 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.54 |
| ▸ | RARA | P10276 | 1/20 | 0.53 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773176 | 1.00 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8983021 | 1.00 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8773119 | 1.00 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8773157 | 1.00 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9850179 | 0.94 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9850118 | 0.94 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9723153 | 0.94 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9850155 | 0.94 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL10482122 | 0.94 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL9850312 | 0.94 | MAPT (0.79) | MAPTRAB9ASMN1; SMN2MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589103-A | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1996-12-31 | — | — | US | disclosed |
| EP-0606090-A1 | Mesomorphic compound, liquid crystal composition containing same, and liquid crystal device using same | CANON KABUSHIKI KAISHA (JP) | 1994-07-13 | — | — | EP | disclosed |