Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.45 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983035 | 1.00 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL19726067 | 1.00 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL9848034 | 1.00 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL18467220 | 0.95 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL9742948 | 0.95 | NR1I2 (0.44) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL18419623 | 0.95 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL18419624 | 0.95 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL8983048 | 0.94 | NR1I2 (0.51) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL8983045 | 0.94 | NR1I2 (0.51) | NR1I2MAPTPPARGALBSLC22A6 | |
| SCHEMBL12969278 | 0.93 | NR1I2 (0.45) | NR1I2MAPTPPARGALBSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409164-B1 | Phenacylpyridiniothiocephalosporins | SHIONOGI & CO (JP) | 1996-06-05 | — | — | EP | disclosed |
| EP-0416410-B1 | Piperaziniocephalosporins | SHIONOGI & CO (JP) | 1994-11-30 | — | — | EP | disclosed |
| US-5143910-A | PIPERAZINIOCEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1992-09-01 | — | — | US | disclosed |
| US-5134138-A | ANTIBIOTICS | SHIONOGI & CO., LTD. (JP) | 1992-07-28 | — | — | US | disclosed |
| EP-0416410-A1 | Piperaziniocephalosporins | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1991-03-13 | — | — | EP | disclosed |