Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | RARB | P10826 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.47 |
| ▸ | RELA | Q04206 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983225 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8982973 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983117 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983140 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8982967 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983128 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983159 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983108 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983101 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB | |
| SCHEMBL8983152 | 1.00 | SMN1; SMN2 (0.52) | SMN1; SMN2KMT2ANPC1RAB9ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5529718-A | Smectic liquid-crystal mixture | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |