Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.57 |
| ▸ | PPARG | P37231 | 9/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983760 | 0.82 | KDR (0.78) | PPARAPPARGKDR | |
| SCHEMBL5855712 | 0.81 | PPARG (0.55) | PPARAPPARGKDRKDM4E | |
| SCHEMBL5855692 | 0.78 | KDR (0.56) | PPARAPPARGKDRKDM4EHPGD | |
| SCHEMBL5857222 | 0.77 | KDR (0.57) | PPARAPPARGKDRKDM4EPOLB | |
| SCHEMBL9091592 | 0.76 | FFAR1 (0.69) | PPARAPPARGKDRPOLB | |
| SCHEMBL31180828 | 0.76 | KDR (0.53) | PPARAPPARGKDRKDM4EPOLB | |
| SCHEMBL9316924 | 0.75 | KDM4E (0.60) | PPARAPPARGKDRKDM4ELMNA | |
| SCHEMBL8859387 | 0.75 | PPARG (0.68) | PPARAPPARG | |
| SCHEMBL5855676 | 0.75 | PPARA (0.80) | PPARAPPARGKDR | |
| SCHEMBL5857239 | 0.74 | PPARA (0.48) | PPARAPPARGKDRKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480896-A | ARALKYL: 4-/2-/N-METHYL-N-/2-BENZOXAZOLYL/AMINO/ETHOXY/BENZYL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-01-02 | — | — | US | disclosed |