Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.45 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1001259 | 0.83 | ABCG2 (0.60) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL27934332 | 0.79 | CA1 (0.55) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL29036841 | 0.78 | KDM4E (0.56) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL30558214 | 0.78 | ABCG2 (0.70) | CA1CA2ABCG2CYP2C9MAPT | |
| SCHEMBL18932159 | 0.78 | ABCG2 (0.70) | CA1CA2ABCG2CYP2C9MAPT | |
| SCHEMBL8983913 | 0.77 | CA1 (0.52) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL27585014 | 0.77 | CA1 (0.52) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL15168326 | 0.77 | CA1 (0.59) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL15528063 | 0.75 | CA1 (0.50) | CA1CA2ABCG2CYP2C9PLA2G2A | |
| SCHEMBL8984020 | 0.75 | KCNA3 (0.51) | CA1CA2ABCG2CYP2C9PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166963-A | Composition containing zinc compound and p-acetaminophenyl acetic acid | XIA XIAOLIN (CN) | 1997-12-10 | — | — | CN | claimed |
| CN-101519378-A | Diaryl pyrimidyl guanidine and preparation method and pharmaceutical use of same | UNIV SHANXI NORMAL | 2009-09-02 | — | — | CN | disclosed |
| CN-1208093-C | Pharmaceutical composition and preparation method thereof | CHINOIN GYOGYSZER ES VEGYESZET (CH) | 2005-06-29 | — | — | CN | disclosed |
| CN-1076195-C | Composition containing zinc compound and p-acetaminophenyl acetic acid | XIA XIAOLIN (CN) | 2001-12-19 | — | — | CN | disclosed |
| CN-1191483-A | Application of isopropoxy isoflavone in reducing CD8+ cell number | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1998-08-26 | — | — | CN | disclosed |
| EP-0710234-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1996-05-08 | — | — | EP | disclosed |
| CN-1105271-A | Pharmaceutical composition and process | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1995-07-19 | — | — | CN | disclosed |
| WO-1995003293-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1995-02-02 | — | — | WO | disclosed |