Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | ALDH2 | P05091 | 14/20 | 0.66 |
| ▸ | MAOA | P21397 | 8/20 | 0.66 |
| ▸ | MAOB | P27338 | 8/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.63 |
| ▸ | STAT1 | P42224 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8983992 | 0.91 | ALDH2 (0.78) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27540611 | 0.89 | MAPT (0.78) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8983857 | 0.88 | ALDH2 (0.64) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8635597 | 0.87 | ALDH2 (0.72) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8983984 | 0.87 | MAPT (0.79) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11556173 | 0.87 | ALDH2 (0.73) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10620423 | 0.87 | ALDH2 (0.79) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8983987 | 0.87 | ALDH2 (0.84) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8983889 | 0.87 | ALDH2 (0.84) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8983891 | 0.86 | MAPT (0.68) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1129445-A | Isoflavone derivatives | CHINOIN GYOGYSZER ES VEGYESZET (HU) | 1996-08-21 | — | — | CN | disclosed |
| EP-0710234-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1996-05-08 | — | — | EP | disclosed |
| WO-1995003293-A1 | ISOFLAVONE DERIVATIVES | CHINOIN LTD. (HU) | 1995-02-02 | — | — | WO | disclosed |