Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 6/20 | 0.42 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | RARA | P10276 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9007133 | 0.90 | S1PR1 (0.47) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL9007107 | 0.90 | S1PR1 (0.49) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL9007184 | 0.90 | S1PR1 (0.47) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL8984284 | 0.83 | CYP3A4 (0.48) | S1PR1S1PR3S1PR4S1PR5KDM4E | |
| SCHEMBL8984295 | 0.82 | RARB (0.47) | RARBRARARARGSPHK2HTR2A | |
| SCHEMBL8984271 | 0.80 | S1PR1 (0.40) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL8769219 | 0.80 | S1PR1 (0.45) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL10986242 | 0.78 | RARB (0.59) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL11059845 | 0.78 | RARB (0.59) | S1PR1RARBRARARARGS1PR3 | |
| SCHEMBL10983916 | 0.78 | RARB (0.59) | S1PR1RARBRARARARGS1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476567-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5217645-A | Low temperature, high speed response | CANON KABUSHIKI KAISHA (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0476567-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1992-03-25 | — | — | EP | disclosed |