Bromide

Bromide

SCHEMBL898427

Oc1ccccc1C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.48
SNCA P37840 2/20 0.47
AKR1B1 P15121 1/20 0.47
HIF1A Q16665 2/20 0.44
CYP2D6 P10635 2/20 0.43
TSHR P16473 2/20 0.43
TAAR1 Q96RJ0 1/20 0.42
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
IDO1 P14902 2/20 0.41
CA12 O43570 2/20 0.41
CA2 P00918 2/20 0.41
PKM P14618 1/20 0.40
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
MPO P05164 1/20 0.39
KEAP1 Q14145 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31208250 0.98 HSPA5 (0.50) HSPA5SNCAAKR1B1HIF1ACYP2D6
Salicyl Alcohol SCHEMBL10383731 0.93 SNCA (0.42) HSPA5SNCAAKR1B1HIF1ACYP2D6
SCHEMBL8375249 0.90 HSPA5 (0.43) HSPA5SNCAAKR1B1HIF1ACYP2D6
SCHEMBL8372345 0.90 HSPA5 (0.43) HSPA5SNCAAKR1B1HIF1ACYP2D6
Bromide SCHEMBL2446627 0.84 HIF1A (0.55) SNCAHIF1ACYP2D6TSHRTAAR1
SCHEMBL8375251 0.82 AKR1B1 (0.40) HSPA5SNCAAKR1B1HIF1ACYP2D6
Hydrochloric Acid SCHEMBL9292231 0.80 HIF1A (0.55) SNCAHIF1ACYP2D6TSHRTAAR1
Bromide SCHEMBL3146027 0.80 SNCA (0.41) SNCAHIF1ACYP2D6TSHRCA9
Bromide SCHEMBL8464686 0.78 HIF1A (0.48) SNCAHIF1ACYP2D6TSHRALDH1A1
Bromide SCHEMBL3150251 0.78 MEN1 (0.56) HSPA5SNCAAKR1B1HIF1ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114249718-A Sulfonium salt derivative and preparation method and medical application thereof 中国药科大学 2022-03-29 CN claimed
US-6248161-B1 Preparation of permanent color inks from water-soluble colorants using specific phosphonium salts HEWLETT-PACKARD COMPANY 2001-06-19 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
US-6086661-A (A)IMIDAZOLINIUM QUATERNARY SALT, (B) PHOSPHONIUM QUATERNARY SALT, OR (C) AN AMMONIUM QUATERNARY SALT; A PAPER-CURL REDUCING COMPOUND; DYE; STABILIZERS, BIOCIDE, WATER SOLUBLE SALT XEROX CORPORATION (US) 2000-07-11 US claimed
US-5760809-A INK JET PRINTING XEROX CORPORATION (US) 1998-06-02 US claimed
US-5709976-A Coated papers XEROX CORPORATION (US) 1998-01-20 US claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0615853-B1 Recording sheets containing phosphonium compounds XEROX CORP (US) 1996-10-16 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0615853-A1 Recording sheets containing phosphonium compounds XEROX CORPORATION (US) 1994-09-21 EP claimed
WO-2026087965-A1 COMPOSITION COMPRISING EPOXY RESIN WITH CONSTRAINED AROMATIC RINGS AND PHOTOBASE 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-04-30 WO disclosed
EP-4656634-A1 EPISULFIDE COMPOSITION, POLYMERIZABLE COMPOSITION, CURED PRODUCT, OPTICAL MATERIAL, AND LENS Mitsui Chemicals, Inc. (JP) 2025-12-03 EP disclosed
WO-2025200154-A1 TWO-PART EPOXY COMPOSITION COMPRISING THIOL CURATIVE, AND CATALYST 3M INNOVATIVE PROPERTIES COMPANY (US) 2025-10-02 WO disclosed
EP-0207605-A1 Hypoglycemic thiazolidinediones PFIZER INC. (US) 1987-01-07 EP disclosed
WO-1986007056-A1 HYPOGLYCEMIC THIAZOLIDINEDIONES PFIZER INC. (US) 1986-12-04 WO disclosed
EP-0169571-A1 Phenylnonatetraenic-acid derivatives, their preparation and pharmaceutical compositions containing them F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1986-01-29 EP disclosed
EP-0026343-B1 PROCESS FOR PREPARING BIS-BENZOFURAN COMPOUNDS HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-22 EP disclosed