Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.39 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8984278 | 0.89 | CYP1A2 (0.39) | CYP3A4ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL8984271 | 0.85 | S1PR1 (0.40) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8984070 | 0.84 | CYP3A4 (0.56) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8984312 | 0.79 | RARB (0.37) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8984281 | 0.78 | RARB (0.42) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL8984284 | 0.77 | CYP3A4 (0.48) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL16552798 | 0.76 | NR5A1 (0.58) | CYP3A4ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL13309870 | 0.76 | NR5A1 (0.58) | CYP3A4ALDH1A1LMNASMN1; SMN2CYP1A2 | |
| SCHEMBL2466020 | 0.76 | HSD17B10 (0.55) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL6418801 | 0.76 | HSD17B10 (0.55) | CYP3A4ALDH1A1LMNASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0476567-B1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KK (JP) | 1996-06-12 | — | — | EP | disclosed |
| US-5217645-A | Low temperature, high speed response | CANON KABUSHIKI KAISHA (JP) | 1993-06-08 | — | — | US | disclosed |
| EP-0476567-A1 | Mesomorphic compound, liquid crystal composition, liquid crystal device, display apparatus and display method | CANON KABUSHIKI KAISHA (JP) | 1992-03-25 | — | — | EP | disclosed |