Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21309293 | 0.79 | ESR1 (0.38) | ESR1ESR2AHRKDM4EMEN1 | |
| SCHEMBL28550889 | 0.78 | ESR1 (0.39) | ESR1ESR2KDM4EMEN1LMNA | |
| SCHEMBL24969145 | 0.77 | ESR1 (0.39) | ESR1ESR2AHRKDM4EMEN1 | |
| SCHEMBL24969320 | 0.77 | ESR1 (0.39) | ESR1ESR2AHRKDM4EMEN1 | |
| SCHEMBL8984822 | 0.76 | ESR1 (0.36) | ESR1ESR2KDM4EMEN1LMNA | |
| SCHEMBL5998195 | 0.74 | KDM4E (0.43) | ESR1ESR2AHRKDM4EMEN1 | |
| SCHEMBL29403370 | 0.74 | KDM4E (0.43) | ESR1ESR2AHRKDM4EMEN1 | |
| SCHEMBL29367681 | 0.74 | KDM4E (0.43) | ESR1ESR2AHRKDM4EMEN1 | |
| SCHEMBL23802657 | 0.74 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL31398851 | 0.74 | ESR1 (0.34) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |