Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.64 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278203 | 0.87 | ESR1 (0.62) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL20590527 | 0.85 | ESR1 (0.59) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL17789202 | 0.84 | ESR1 (0.63) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL24183985 | 0.82 | ESR1 (0.55) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL20590542 | 0.82 | ESR1 (0.50) | ESR1ESR2KMT2AMAPTALDH1A1 | |
| SCHEMBL17789220 | 0.80 | ESR1 (0.58) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL2858096 | 0.79 | ESR1 (0.57) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL5446714 | 0.79 | ESR1 (0.53) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL21547754 | 0.79 | ESR2 (0.53) | ESR1ESR2KMT2AMAPTNPSR1 | |
| SCHEMBL21547755 | 0.79 | ESR1 (0.53) | ESR1ESR2KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578737-A | SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS | THE DOW CHEMICAL COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5387725-A | Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst | THE DOW CHEMICAL COMPANY (US) | 1995-02-07 | — | — | US | disclosed |