Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1756779 | 0.75 | KMT2A (0.50) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL432657 | 0.74 | KMT2A (0.49) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL6069998 | 0.73 | KMT2A (0.48) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL5109854 | 0.72 | MEN1 (0.71) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL1000788 | 0.72 | MEN1 (0.71) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL7424105 | 0.72 | MEN1 (0.71) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL3970912 | 0.72 | MEN1 (0.76) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL4814264 | 0.72 | MEN1 (0.76) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL7393652 | 0.72 | MEN1 (0.76) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 | |
| SCHEMBL379160 | 0.72 | MEN1 (0.76) | P2RX4KMT2AMEN1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5482947-A | ENZYME INHIBITORS FOR HIV PROTEASE INHIBITION FROM UREA OR THIOUREA COMPOUNDS | TALLEY JOHN J (US) | 1996-01-09 | — | — | US | claimed |