SCHEMBL8985120

SCHEMBL8985120

O=C1CCCCC1(C1=CCCCC1)C1=CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HCAR2 Q8TDS4 2/20 0.36
CYP19A1 P11511 6/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.33
HCAR3 P49019 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL788174 0.73 MEN1 (0.41) MEN1KMT2AHCAR2CYP19A1HCAR3
SCHEMBL6246587 0.70 GRIN2D (0.35) MEN1KMT2AHCAR2CYP19A1ALDH1A1
SCHEMBL6247782 0.68 GRIN2D (0.36) MEN1KMT2AHCAR2CYP19A1HCAR3
SCHEMBL5550605 0.67 GRIN2D (0.38) MEN1KMT2AHCAR2CYP19A1ALDH1A1
SCHEMBL6251171 0.67 GRIN2D (0.44) MEN1KMT2AHCAR2CYP19A1HCAR3
SCHEMBL8965563 0.67 MEN1 (0.34) MEN1KMT2AHCAR2
SCHEMBL28696460 0.67 MEN1 (0.41) MEN1KMT2AHCAR2CYP19A1HCAR3
SCHEMBL4426108 0.67 HCAR2 (0.35) MEN1KMT2AHCAR2
SCHEMBL11126428 0.67 MEN1 (0.34) MEN1KMT2A
SCHEMBL793523 0.67 HCAR2 (0.35) MEN1KMT2AHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564040-B1 Two-step process for liquid-phase production of oximes ENICHEM SPA (IT) 1996-05-22 EP disclosed
EP-0496385-B1 Multistep process for the liquid phase ammoximation of carbonyl compounds ENICHEM SPA (IT) 1995-04-05 EP disclosed
US-5312987-A Two-step process for liquid-phase production of oximes ENICHEM ANIC S.R.L. (IT) 1994-05-17 US disclosed
EP-0564040-A2 Two-step process for liquid-phase production of oximes ENICHEM S.p.A. (IT) 1993-10-06 EP disclosed
US-5227525-A MULTISTEP PROCESS FOR THE LIQUID PHASE AMMOXIMATION OF CARBONYL COMPOUNDS ENICHEM ANIC S.R.L. (IT) 1993-07-13 US disclosed
EP-0496385-A1 Multistep process for the liquid phase ammoximation of carbonyl compounds ENICHEM S.p.A. (IT) 1992-07-29 EP disclosed