Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29700132 | 0.87 | GAA (0.49) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL11250544 | 0.85 | TSHR (0.48) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL29700206 | 0.80 | AOC3 (0.55) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL12243879 | 0.72 | AOC3 (0.53) | GAAAOC3TSHRMAPK1HIF1A | |
| SCHEMBL21353864 | 0.72 | AOC3 (0.44) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL21353865 | 0.72 | AOC3 (0.44) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL27130324 | 0.71 | AOC3 (0.47) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL27006320 | 0.71 | AOC3 (0.47) | GAAAOC3TSHRTP53MAPK1 | |
| SCHEMBL29570287 | 0.70 | AOC3 (0.47) | GAAAOC3TSHRHIF1ALMNA | |
| SCHEMBL29571171 | 0.69 | AOC3 (0.55) | GAAAOC3LMNAGABBR2GABBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8217757-A | — | — | None | — | — | JP | disclosed |
| JP-H08217757-A | INSECTICIDAL COMPOSITION CONTAINING A NOVEL PYRIMIDINE DERIVATIVE AS A SYBERGIST | NISSAN CHEM IND LTD | 1996-08-27 | — | — | JP | disclosed |