Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | BCHE | P06276 | 6/20 | 0.56 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20314086 | 0.92 | PRMT5 (0.57) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL9117138 | 0.90 | BCHE (0.52) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL20314089 | 0.89 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL8985561 | 0.87 | SMN1; SMN2 (0.62) | MEN1KMT2ASMN1; SMN2BCHENR4A2 | |
| SCHEMBL8985574 | 0.87 | KDM1A (0.57) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL20314091 | 0.87 | MEN1 (0.57) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL8985630 | 0.82 | TP53 (0.58) | MEN1KMT2ABCHECXCR4NR4A2 | |
| SCHEMBL21634323 | 0.82 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2MAPK1HTT | |
| SCHEMBL20314088 | 0.81 | BCHE (0.62) | MEN1KMT2AMAPK1BCHESPHK2 | |
| SCHEMBL20325087 | 0.80 | BCHE (0.53) | MEN1KMT2ASMN1; SMN2MAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5550292-A | ANXIOLYTIC AND ANTIDEPRESSANT AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-08-27 | — | — | US | disclosed |
| EP-0666840-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-08-16 | — | — | EP | disclosed |
| WO-1995006630-A1 | BENZYLAMINE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-09 | — | — | WO | disclosed |