⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13819454 | 0.79 | HDAC3 (0.56) | — | |
| SCHEMBL1146799 | 0.77 | — | — | |
| SCHEMBL13590067 | 0.75 | ACE (0.39) | — | |
| SCHEMBL10345078 | 0.73 | — | — | |
| SCHEMBL12316251 | 0.73 | — | — | |
| SCHEMBL14271512 | 0.72 | — | — | |
| SCHEMBL930337 | 0.71 | — | — | |
| SCHEMBL1962359 | 0.71 | — | — | |
| SCHEMBL18625754 | 0.71 | — | — | |
| SCHEMBL13302387 | 0.69 | HDAC3 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2177236-B1 | A METHOD FOR THE FORMATION OF A RAPID-GELLING BIOCOMPATIBLE HYDROGEL AND THE PREPARATION OF A SPRAYING AGENT | BIOREGEN BIOMEDICAL CHANGZHOU (CN) | 2016-11-02 | — | — | EP | disclosed |
| US-8647670-B2 | Biocompatible rapid-gelating hydrogel and associated preparation method of spray | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2014-02-11 | — | — | US | disclosed |
| US-8647670-B2 | Biocompatible rapid-gelating hydrogel and associated preparation method of spray | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2014-02-11 | — | — | US | disclosed |
| US-8188216-B2 | Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery | TRANZYME PHARMA INC. (CA) | 2012-05-29 | — | — | US | disclosed |
| US-20100144902-A1 | BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2010-06-10 | — | — | US | disclosed |
| US-20100144902-A1 | BIOCOMPATIBLE RAPID-GELATING HYDROGEL AND ASSOCIATED PREPARATION METHOD OF SPRAY | BIOREGEN BIOMEDICAL (CHANGZHOU) CO., LTD. (CN) | 2010-06-10 | — | — | US | disclosed |