Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 10/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 2/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9050803 | 0.91 | NPY1R (0.52) | NPY1RKMT2AMEN1METNCOA1 | |
| SCHEMBL9050312 | 0.90 | NPY1R (0.51) | NPY1RMETNCOA1NCOA3POLB | |
| SCHEMBL9051710 | 0.86 | NPY1R (0.66) | NPY1RKMT2AMEN1NCOA1NCOA3 | |
| SCHEMBL9051463 | 0.85 | NPY1R (0.68) | NPY1RRAB9AMETALDH1A1LMNA | |
| SCHEMBL10904937 | 0.83 | NPY1R (0.55) | NPY1RKMT2AMEN1RAB9AMET | |
| SCHEMBL9050400 | 0.83 | NPY1R (0.65) | NPY1RKMT2AMEN1METNCOA1 | |
| SCHEMBL9050676 | 0.83 | NPY1R (0.65) | NPY1RKMT2AMEN1METNCOA1 | |
| SCHEMBL9050776 | 0.83 | NPY1R (0.47) | NPY1RKMT2AMEN1METNCOA1 | |
| SCHEMBL9050428 | 0.82 | NPY1R (0.56) | NPY1RKMT2AMEN1METNCOA1 | |
| SCHEMBL9052048 | 0.81 | NPY1R (0.50) | NPY1RKMT2AMEN1METNCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552411-A | HYPOTENSIVE, ANTIOBESITY | WARNER-LAMBERT COMPANY (US) | 1996-09-03 | — | — | US | disclosed |