⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29837279 | 1.00 | — | — | |
| SCHEMBL27982386 | 0.98 | QPCT (0.50) | — | |
| SCHEMBL2447586 | 0.98 | QPCT (0.50) | — | |
| SCHEMBL2447581 | 0.98 | QPCT (0.50) | — | |
| Hydrazine SCHEMBL3450713 | 0.96 | QPCT (0.49) | — | |
| SCHEMBL28135793 | 0.86 | QPCT (0.49) | — | |
| SCHEMBL67119 | 0.82 | — | — | |
| SCHEMBL29602491 | 0.82 | — | — | |
| Alanine SCHEMBL28113518 | 0.80 | NAMPT (0.40) | — | |
| Bromide SCHEMBL4711523 | 0.80 | KDM4A (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3051 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250388599-A1 | TRICYCLIC PI3K INHIBITOR COMPOUNDS AND METHODS OF USE | GENENTECH INC (US) | 2025-12-25 | — | — | US | claimed |
| WO-2025129023-A1 | INDOLE AMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | RECTIFY PHARMACEUTICALS, INC. (US) | 2025-06-19 | — | — | WO | claimed |
| CN-116262207-B | Method for electrochemically synthesizing metal-organic framework membrane and application of metal-organic framework membrane in gas separation | 中国科学院大连化学物理研究所 | 2025-05-16 | — | — | CN | claimed |
| CN-118546138-A | 3H-imidazo [4,5-C ] pyridine pleuromutilin onium salt derivatives, and preparation method and application thereof | 西安康诺化工有限公司 | 2024-08-27 | — | — | CN | claimed |
| US-20240246905-A1 | VINYL ISOCYANIDE COMPOUNDS AS ANTIBACTERIAL AGENTS | UNIVERSITY OF LEICESTER (GB) | 2024-07-25 | — | — | US | claimed |
| CN-118344611-A | Method for preparing micro-nano metal organic framework by oil-water two-phase method and application | 广西师范大学 | 2024-07-16 | — | — | CN | claimed |
| CN-118142356-A | Method for preparing ultrathin metal-organic framework film by steam-assisted in-situ conversion and separation application thereof | 中国科学院大连化学物理研究所 | 2024-06-07 | — | — | CN | claimed |
| CN-116535616-A | Phosphorus-containing imidazole oligomer flame-retardant curing agent and application thereof in flame-retardant epoxy resin | 浙大宁波理工学院 | 2023-08-04 | — | — | CN | claimed |
| US-20230227458-A1 | IRREVERSIBLE INHIBITORS OF MENIN-MLL INTERACTION | BIOMEA FUSION, INC. | 2023-07-20 | — | — | US | claimed |
| CN-116262207-A | Method for electrochemically synthesizing metal-organic framework membrane and application of metal-organic framework membrane in gas separation | 中国科学院大连化学物理研究所 | 2023-06-16 | — | — | CN | claimed |
| EP-2238144-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB Pharma, S.A. (BE) | 2010-10-13 | — | — | EP | claimed |
| US-20100233164-A1 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS FOR THE TREATMENT OF HEMATOPOIETIC MALIGNANCIES | GENENTECH, INC. | 2010-09-16 | — | — | US | claimed |
| WO-2010105008-A2 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS FOR THE TREATMENT OF HEMATOPOIETIC MALIGNANCIES | GENENTECH, INC. (US) | 2010-09-16 | — | — | WO | claimed |
| EP-2205242-A2 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE | Genentech, Inc. (US) | 2010-07-14 | — | — | EP | claimed |
| WO-2009092764-A1 | COMPOUNDS COMPRISING A CYCLOBUTOXY GROUP | UCB PHARMA, S.A. (BE) | 2009-07-30 | — | — | WO | claimed |
| US-20090098135-A1 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE | GENENTECH, INC. | 2009-04-16 | — | — | US | claimed |
| WO-2009036082-A2 | COMBINATIONS OF PHOSPHOINOSITIDE 3-KINASE INHIBITOR COMPOUNDS AND CHEMOTHERAPEUTIC AGENTS, AND METHODS OF USE | GENENTECH, INC. (US) | 2009-03-19 | — | — | WO | claimed |
| WO-2008140239-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-11-20 | — | — | WO | claimed |
| US-6858393-B1 | Chain terminators for DNA synthesis | STRATAGENE CALIFORNIA (US) | 2005-02-22 | — | — | US | claimed |
| US-4329459-A | ENDOPEROXIDE CYCLOXGENASE INHIBITORS | THE UPJOHN COMPANY (US) | 1982-05-11 | — | — | US | claimed |