Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8986924 | 0.81 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8636517 | 0.80 | SLC6A4 (0.50) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8727070 | 0.78 | PTPN1 (0.55) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8727063 | 0.78 | PTPN1 (0.55) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL8986920 | 0.78 | SLC6A4 (0.47) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL31545989 | 0.76 | SLC6A4 (0.59) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL3123300 | 0.74 | SLC6A4 (0.58) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL21807707 | 0.74 | SLC6A4 (0.58) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL2553015 | 0.73 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2 | |
| SCHEMBL2553013 | 0.73 | SLC6A4 (0.66) | SLC6A4TAAR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717746-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007284-A1 | PHOSPHINIC ACID DERIVATIVES WITH ANTI-HYPER GLYCEMIC AND/OR ANTI-OBESITY ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 1995-03-16 | — | — | WO | disclosed |