Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 8/20 | 0.49 |
| ▸ | RARA | P10276 | 2/20 | 0.49 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9563700 | 1.00 | HDAC3 (0.50) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9563803 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9493032 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9493897 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9493571 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9563877 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9493588 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9495390 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9493350 | 0.98 | RARB (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL7786808 | 0.98 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501268-B1 | Liquid crystal compounds ending with a 1-alkinyl group | HOFFMANN LA ROCHE (CH) | 1996-06-12 | — | — | EP | disclosed |
| US-5328637-A | Electrooptical devices; deformation of aligned phases and supertwisted nematic applications; miscibility, solubility | HOFFMANN-LA ROCHE INC. (US) | 1994-07-12 | — | — | US | disclosed |
| US-5273680-A | A chiral tilted smectic liquid crystal based on terphenyls | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1993-12-28 | — | — | US | disclosed |
| EP-0329752-B1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0501268-A2 | Liquid crystal compounds ending with a 1-alkinyl group | F. HOFFMANN-LA ROCHE AG (CH) | 1992-09-02 | — | — | EP | disclosed |
| EP-0329752-A1 | FLUORINATED OLIGOPHENYLS AND THEIR USE IN LIQUID CRYSTAL MATERIALS | MERCK PATENT GmbH (DE) | 1989-08-30 | — | — | EP | disclosed |