⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18869382 | 0.85 | — | — | |
| SCHEMBL14943267 | 0.80 | — | — | |
| SCHEMBL879246 | 0.69 | — | — | |
| SCHEMBL4431350 | 0.69 | — | — | |
| SCHEMBL21095750 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL22776042 | 0.67 | CHRNA7 (0.33) | — | |
| SCHEMBL12627038 | 0.65 | CHRNA7 (0.35) | — | |
| SCHEMBL16933654 | 0.65 | CHRNA7 (0.35) | — | |
| SCHEMBL875052 | 0.64 | — | — | |
| SCHEMBL19465125 | 0.64 | CYP2C9 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494918-A | ANTICHOLESTEROL AGENTS | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1996-02-27 | — | — | US | disclosed |
| US-5385912-A | Hypocholesterolemic or hypolipidemic agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1995-01-31 | — | — | US | disclosed |
| WO-1992015579-A1 | MULTICYCLIC TERTIARY AMINE POLYAROMATIC SQUALENE SYNTHETASE INHIBITORS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-09-17 | — | — | WO | disclosed |