Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14228880 | 0.89 | GRM5 (0.41) | RARBFFAR1GRM5CNR1CNR2 | |
| SCHEMBL13211613 | 0.89 | RARB (0.51) | RARBACACBHSD17B10FDFT1 | |
| SCHEMBL19845067 | 0.89 | ESR1 (0.42) | RARBFFAR1CNR1CNR2ALOX5 | |
| SCHEMBL29306100 | 0.89 | TSHR (0.46) | RARBHSD17B10KDM1A | |
| SCHEMBL14525801 | 0.89 | RARB (0.40) | RARBFFAR1CNR1CNR2CHKA | |
| SCHEMBL8378004 | 0.88 | RARB (0.48) | RARBMAOBCNR1CNR2CHKA | |
| SCHEMBL9334037 | 0.87 | CYP1A1 (0.41) | RARBCNR1CNR2CHKAALOX5 | |
| SCHEMBL9335246 | 0.86 | RARB (0.40) | RARBFFAR1CNR1CNR2CHKA | |
| SCHEMBL9399967 | 0.84 | RARB (0.52) | RARBCNR1CNR2CHKAALOX5 | |
| SCHEMBL14228619 | 0.84 | RARB (0.39) | RARBFFAR1CNR1CNR2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8217706-A | — | — | None | — | — | JP | disclosed |
| JP-H08217706-A | 2-FLUOROBIPHENYL DERIVATIVE | DAINIPPON INK & CHEM INC | 1996-08-27 | — | — | JP | disclosed |