Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989083 | 0.87 | HSD17B10 (0.40) | — | |
| SCHEMBL8988953 | 0.85 | CYP2D6 (0.30) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8988989 | 0.85 | CYP2D6 (0.30) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8988848 | 0.85 | — | — | |
| SCHEMBL8989025 | 0.83 | — | — | |
| SCHEMBL8988962 | 0.83 | CYP2D6 (0.32) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8988824 | 0.82 | CYP2D6 (0.31) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8989136 | 0.81 | CYP2D6 (0.30) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8988878 | 0.80 | CYP2D6 (0.30) | CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8989098 | 0.79 | HSD17B10 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5488140-A | ANTICONVULSANTS | CIBA-GEIGY CORPORATION (US) | 1996-01-30 | — | — | US | disclosed |
| US-5294734-A | 1-phosphato-4-amino-pent-2-enoic acids and derivatives | CIBA-GEIGY CORP. (US) | 1994-03-15 | — | — | US | disclosed |