⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942915 | 0.90 | — | — | |
| SCHEMBL16587911 | 0.85 | — | — | |
| SCHEMBL8943195 | 0.84 | — | — | |
| SCHEMBL8942884 | 0.84 | — | — | |
| SCHEMBL8943292 | 0.84 | — | — | |
| SCHEMBL8943091 | 0.84 | — | — | |
| SCHEMBL8943639 | 0.83 | — | — | |
| SCHEMBL8943457 | 0.83 | — | — | |
| SCHEMBL8943903 | 0.83 | — | — | |
| SCHEMBL8943431 | 0.83 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188281-B2 | Azaindoles useful as inhibitors of JAK and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2012-05-29 | — | — | US | disclosed |
| US-20090176763-A1 | Azaindoles useful as inhibitors of JAK and other protein kinases | VERTEX PHARMACEUTICALS INCORPORATED | 2009-07-09 | — | — | US | disclosed |