⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378551 | 0.81 | — | — | |
| SCHEMBL27943300 | 0.81 | CYP1A2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL7856022 | 0.78 | TSHR (0.42) | — | |
| SCHEMBL9355736 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL27175232 | 0.72 | — | — | |
| SCHEMBL17286403 | 0.70 | — | — | |
| SCHEMBL11325428 | 0.70 | — | — | |
| SCHEMBL26256153 | 0.70 | — | — | |
| SCHEMBL943724 | 0.70 | — | — | |
| SCHEMBL30725579 | 0.70 | KCNH2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230287204-A1 | OXIDIZED POLYISOBUTENE COMPOUNDS AND METHODS OF MAKING THE SAME | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2023-09-14 | — | — | US | disclosed |
| US-9738677-B2 | Amphotericin B derivative with reduced toxicity | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2017-08-22 | — | — | US | disclosed |
| US-20170088572-A1 | AMPHOTERICIN B DERIVATIVE WITH REDUCED TOXICITY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-30 | — | — | US | disclosed |
| EP-2842944-B1 | METHOD FOR PRODUCING NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | NIPPON SODA CO (JP) | 2017-03-15 | — | — | EP | disclosed |
| EP-2621903-B1 | N-HETEROARYL COMPOUNDS | INTERVET INT BV (NL) | 2017-03-01 | — | — | EP | disclosed |
| EP-2557078-B1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND AND METHOD FOR PRODUCING SAME | NIPPON SODA CO (JP) | 2016-03-23 | — | — | EP | disclosed |
| EP-2730561-B1 | Methods to prepare haloalkyl nitrogen-containing heterocyclic compounds | NIPPON SODA CO (JP) | 2015-10-14 | — | — | EP | disclosed |
| US-8981107-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD. (JP) | 2015-03-17 | — | — | US | disclosed |
| EP-2842944-A1 | Method for producing nitrogen-containing heterocyclic compound | NIPPON SODA CO., LTD. (JP) | 2015-03-04 | — | — | EP | disclosed |
| US-8962850-B2 | Nitrogen-containing heterocyclic compound and method for producing same | NIPPON SODA CO., LTD. (JP) | 2015-02-24 | — | — | US | disclosed |
| CN-1037141-A | The alkylamine derivative that replaces | BANYU PHARMA CO LTD (JP) | 1989-11-15 | — | — | CN | disclosed |
| EP-0318860-A2 | Substituted alkylamine derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| US-4826833-A | ANTIBIOTICS | PFIZER INC. (US) | 1989-05-02 | — | — | US | disclosed |
| CN-85101572-A | Process for producing 6- (substituted) methylenepenicillanic acids, 6- (substituted) hydroxymethylpenicillanic acids and derivatives thereof | — | 1986-10-29 | — | — | CN | disclosed |
| US-4585871-A | Process for oxidizing halopyridines to halopyridine-N-oxides | OLIN CORPORATION (US) | 1986-04-29 | — | — | US | disclosed |
| US-4576629-A | Herbicidal thiadiazole ureas | UNION CARBIDE CORPORATION (US) | 1986-03-18 | — | — | US | disclosed |
| EP-0150984-A2 | 6-(Substituted) methylenepenicillanic and 6-(substituted) hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4504667-A | Process for oxidizing halopyridines to halopyridine-N-oxides | OLIN CORPORATION (US) | 1985-03-12 | — | — | US | disclosed |
| EP-0090177-A1 | Process for oxidizing halopyridines to halopyridine-N-oxides | OLIN CORPORATION (US) | 1983-10-05 | — | — | EP | disclosed |
| EP-0036638-A2 | Herbicidal and plant growth regulant 2-sulfinyl and 2-sulfonyl pyridine N-oxides | DIAMOND SHAMROCK CORPORATION (US) | 1981-09-30 | — | — | EP | disclosed |