Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7781274 | 0.86 | HTR2A (0.45) | SLC6A4DRD2SIGMAR1 | |
| SCHEMBL7078580 | 0.86 | HRH3 (0.47) | SLC6A4SLC6A3 | |
| SCHEMBL7781178 | 0.84 | KDM1A (0.45) | SLC6A4DRD2SIGMAR1 | |
| SCHEMBL7073081 | 0.81 | GRIN2B (0.38) | PRCPCCR5SLC6A4 | |
| SCHEMBL7074984 | 0.81 | MC4R (0.44) | — | |
| SCHEMBL8989718 | 0.81 | KDM1A (0.39) | SLC6A4SLC6A3DRD2 | |
| SCHEMBL7073067 | 0.81 | KDM1A (0.39) | SLC6A4SLC6A3DRD2 | |
| SCHEMBL7480872 | 0.81 | KDM1A (0.39) | SLC6A4SLC6A3DRD2 | |
| SCHEMBL7071917 | 0.80 | KDM1A (0.51) | SLC6A3DRD2SIGMAR1 | |
| SCHEMBL7781788 | 0.79 | SLC18A3 (0.50) | SLC6A4SLC6A3DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0646110-B1 | N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS | BASF AG (DE) | 1996-10-23 | — | — | EP | disclosed |
| US-5521209-A | N-substituted azabicyclo[3.2.0]heptane derivatives as neuroleptics, the preparation and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-28 | — | — | US | disclosed |
| EP-0646110-A1 | N-SUBSTITUED 3-AZABICYCLO 3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. | BASF AG (DE) | 1995-04-05 | — | — | EP | disclosed |
| WO-1994000431-A1 | N-SUBSTITUED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS ETC. | BASF AKTIENGESELLSCHAFT (DE) | 1994-01-06 | — | — | WO | disclosed |