Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | CPA1 | P15085 | 1/20 | 0.49 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
| ▸ | ANPEP | P15144 | 2/20 | 0.49 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.49 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108501 | 0.84 | ACE (0.55) | CNR2MMEACECPA1ACE2 | |
| SCHEMBL27587469 | 0.81 | ERAP1 (0.49) | CNR2ANPEPERAP1ERAP2TSHR | |
| SCHEMBL25432477 | 0.80 | EPHX1 (0.58) | MMEACECPA1ACE2EPHX1 | |
| SCHEMBL341788 | 0.80 | ANPEP (0.52) | CNR2MMEANPEPERAP1ERAP2 | |
| SCHEMBL8240623 | 0.80 | EPHX1 (0.58) | MMEACECPA1ACE2EPHX1 | |
| SCHEMBL28107772 | 0.80 | ERAP1 (0.52) | CNR2ANPEPERAP1ERAP2TSHR | |
| SCHEMBL4024544 | 0.78 | ERAP1 (0.55) | CNR2ANPEPERAP1ERAP2TSHR | |
| SCHEMBL5431087 | 0.78 | ERAP1 (0.55) | CNR2ANPEPERAP1ERAP2TSHR | |
| SCHEMBL30136523 | 0.78 | ERAP1 (0.51) | CNR2ANPEPERAP1ERAP2TSHR | |
| SCHEMBL7356925 | 0.78 | ERAP1 (0.55) | CNR2ANPEPERAP1ERAP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110452138-A | A method of preparing N- phenyl -3- methanesulfonyl propionamide | UNIV CHANGZHOU | 2019-11-15 | — | — | CN | claimed |
| CN-109232476-A | A kind of new method preparing N- phenyl -3- morpholine propionamide | 常州大学 | 2019-01-18 | — | — | CN | claimed |
| CN-110452138-A | A method of preparing N- phenyl -3- methanesulfonyl propionamide | UNIV CHANGZHOU | 2019-11-15 | — | — | CN | disclosed |
| CN-110452138-A | A method of preparing N- phenyl -3- methanesulfonyl propionamide | UNIV CHANGZHOU | 2019-11-15 | — | — | CN | disclosed |
| CN-109232476-A | A kind of new method preparing N- phenyl -3- morpholine propionamide | 常州大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-109232476-A | A kind of new method preparing N- phenyl -3- morpholine propionamide | 常州大学 | 2019-01-18 | — | — | CN | disclosed |
| US-5563250-A | Cleavable conjugates for the delivery and release of agents in native form | NEORX CORPORATION (US) | 1996-10-08 | — | — | US | disclosed |
| US-5141648-A | Methods for isolating compounds using cleavable linker bound matrices | NEORX CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |
| EP-0318948-B1 | CLEAVABLE IMMUNOCONJUGATES FOR THE DELIVERY AND RELEASE OF AGENTS IN NATIVE FORM | NEORX CORPORATION (US) | 1992-08-19 | — | — | EP | disclosed |
| US-5017693-A | Methods for introducing a sulfhydryl amino or hydroxyl groups to a compound | NEORX CORPORATION (US) | 1991-05-21 | — | — | US | disclosed |
| EP-0318948-A2 | Cleavable immunoconjugates for the delivery and release of agents in native form | NEORX CORPORATION (US) | 1989-06-07 | — | — | EP | disclosed |