Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 7/20 | 0.39 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | VCP | P55072 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HK1 | P19367 | 1/20 | 0.32 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990463 | 0.90 | CYP2C19 (0.43) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 | |
| SCHEMBL9537324 | 0.86 | HDAC1 (0.38) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 | |
| SCHEMBL9390857 | 0.81 | SLC29A1 (0.36) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 | |
| SCHEMBL9540469 | 0.75 | HPRT1 (0.53) | HIF1ACYP3A4ALDH1A1HPRT1MEN1 | |
| SCHEMBL9172527 | 0.71 | MGMT (0.42) | CYP3A4HPRT1LMNA | |
| SCHEMBL8816222 | 0.70 | SLC29A1 (0.39) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 | |
| SCHEMBL10647050 | 0.69 | MGMT (0.40) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 | |
| SCHEMBL9537658 | 0.69 | BLM (0.65) | HIF1ACYP3A4ALDH1A1HPRT1MEN1 | |
| SCHEMBL10405081 | 0.68 | HIF1A (0.54) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 | |
| SCHEMBL8990330 | 0.68 | HDAC1 (0.38) | CYP1A2CYP2C19HIF1ACYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532225-A | TREATMENT OF HERPES VIRUS | SRI INTERNATIONAL (US) | 1996-07-02 | — | — | US | disclosed |