Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.57 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | GCGR | P47871 | 1/20 | 0.42 |
| ▸ | MPL | P40238 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22881604 | 0.95 | RARB (0.56) | RARBFDFT1GRM2HTR2ARARA | |
| SCHEMBL8990700 | 0.95 | RARB (0.63) | RARBFDFT1GRM2HTR2ARARA | |
| SCHEMBL9223580 | 0.94 | RARB (0.64) | RARBFDFT1GRM2HTR2ARARA | |
| SCHEMBL9221831 | 0.92 | RARB (0.67) | RARBFDFT1HTR2ARARARARG | |
| SCHEMBL17108402 | 0.92 | RARB (0.63) | RARBFDFT1GRM2HTR2ARARA | |
| SCHEMBL8990707 | 0.92 | RARB (0.56) | RARBFDFT1RARARARGMPL | |
| SCHEMBL9228401 | 0.92 | RARB (0.67) | RARBFDFT1HTR2ARARARARG | |
| SCHEMBL9226858 | 0.92 | RARB (0.67) | RARBFDFT1HTR2ARARARARG | |
| SCHEMBL9227894 | 0.92 | RARB (0.67) | RARBFDFT1HTR2ARARARARG | |
| SCHEMBL9225500 | 0.92 | RARB (0.67) | RARBFDFT1HTR2ARARARARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496499-A | Biphenylethanes and liquid-crystalline phase | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-03-05 | — | — | US | disclosed |
| EP-0429558-B1 | DIPHENYLYLETHANES AND LIQUID CRYSTALLINE PHASE | MERCK PATENT GMBH (DE) | 1994-03-30 | — | — | EP | disclosed |