SCHEMBL8991257

SCHEMBL8991257

O=C1CCN1[SiH3]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2518868 0.78
SCHEMBL3000674 0.74
SCHEMBL11135220 0.67
SCHEMBL7771357 0.67
SCHEMBL9600797 0.64
SCHEMBL9020643 0.64
SCHEMBL5771675 0.64
SCHEMBL9020969 0.64
SCHEMBL10969484 0.64
SCHEMBL7771362 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4960880-A STEREOSPECIFIC SYNTHESIS OF B-LACTAM INTERMEDIATES SHIONOGI & CO., LTD. (JP) 1990-10-02 US claimed
EP-0734390-A1 PROCESS FOR THE PREPARATION OF A THIAZOLINE-AZETIDINONE BIOCHIMICA OPOS SPA (IT) 1996-10-02 EP disclosed
EP-0419215-B1 Process for preparing 4-substituted azetidinones LILLY CO ELI (US) 1996-07-24 EP disclosed
WO-1996011202-A1 PROCESS FOR THE PREPARATION OF A THIAZOLINE-AZETIDINONE BIOCHIMICA OPOS S.P.A. (IT) 1996-04-18 WO disclosed
EP-0088488-B1 ANTIBACTERIAL AGENTS, THEIR PREPARATION AND USE BEECHAM GROUP PLC (GB) 1986-10-01 EP disclosed
EP-0088488-A1 Antibacterial agents, their preparation and use BEECHAM GROUP PLC (GB) 1983-09-14 EP disclosed