Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17443158 | 0.86 | CA1 (0.46) | CA1CA2KMT2A | |
| SCHEMBL5006830 | 0.84 | KDM4E (0.42) | KDM4ECA1CA2KMT2AALDH1A1 | |
| SCHEMBL29228948 | 0.82 | KDM4E (0.41) | KDM4ECA1CA2KMT2AALDH1A1 | |
| SCHEMBL15388571 | 0.81 | KDM4E (0.39) | KDM4EKMT2AALDH1A1MAPTUSP2 | |
| SCHEMBL709157 | 0.77 | CA12 (0.45) | KDM4ECA1CA2ALDH1A1MAPT | |
| SCHEMBL27263918 | 0.76 | CA12 (0.43) | KDM4ECA1CA2ALDH1A1MAPT | |
| SCHEMBL27416946 | 0.74 | CA1 (0.36) | CA1CA2 | |
| Water SCHEMBL27737003 | 0.74 | CA12 (0.42) | KDM4ECA1CA2ALDH1A1MAPT | |
| SCHEMBL28106637 | 0.73 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL29998153 | 0.73 | KDM4E (0.46) | KDM4EKMT2AALDH1A1MAPTUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110346316-A | It is coupled the method and assay kit of pyruvate oxidation enzymatic determination sialic acid (SIA) | 浙江力耐得传动科技有限公司 | 2019-10-18 | — | — | CN | claimed |
| CN-110366431-A | Maytansinoid derivatives with self-cleaving peptide linker and conjugates thereof | 伊缪诺金公司 | 2019-10-22 | — | — | CN | disclosed |
| CN-106443006-A | Methods and compositions comprising non-natural amino acids | AMBRX公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-105669593-A | Barium base metal organic framework material preparation method | 中国科学院大连化学物理研究所 | 2016-06-15 | — | — | CN | disclosed |
| EP-0717645-A1 | REDUCTION OF SKIN IRRITATION AND RESISTANCE DURING ELECTROTRANSPORT | ALZA CORPORATION (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995006497-A1 | REDUCTION OF SKIN IRRITATION AND RESISTANCE DURING ELECTROTRANSPORT | ALZA CORPORATION (US) | 1995-03-09 | — | — | WO | disclosed |