Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321565 | 1.00 | PDE4A (0.52) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL9323008 | 0.96 | PDE4A (0.52) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL13727651 | 0.94 | PDE4A (0.47) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL8763069 | 0.94 | PDE4A (0.50) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL3517475 | 0.94 | PDE4A (0.50) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL8763108 | 0.94 | PDE4A (0.50) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL3517791 | 0.94 | PDE4A (0.50) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL8762542 | 0.94 | PDE4A (0.50) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL8763289 | 0.94 | PDE4A (0.50) | PDE4ALMNAUSP2ALDH1A1MEN1 | |
| SCHEMBL3515150 | 0.92 | PDE4A (0.48) | PDE4ALMNAUSP2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5139784-A | For moisturizing and/or softening dry skin | REVLON, INC. (US) | 1992-08-18 | — | — | US | claimed |
| JP-1143891-A | — | — | None | — | — | JP | disclosed |
| JP-1143890-A | — | — | None | — | — | JP | disclosed |
| EP-0447064-B1 | Alkyl diamides and cosmetic treating compositions therewith | REVLON CONSUMER PROD CORP (US) | 1996-07-24 | — | — | EP | disclosed |
| EP-0312086-B1 | Polysulfuric esters of amides of bis-aldonic acids and their derivatives, a method for their preparation and a drug | LUITPOLD PHARMA GMBH (DE) | 1994-02-02 | — | — | EP | disclosed |
| EP-0312087-B1 | AMIDES OF BIS-ALDONIC ACIDS AND A METHOD FOR THEIR PREPARATION | LUITPOLD PHARMA GmbH (DE) | 1993-09-15 | — | — | EP | disclosed |
| US-5037973-A | Hydroxy containing amides, optionally with sugar units, intermediates for polysulfuric acid esters, pharmaceuticals | LUITPOLD-WERK CHEMISCH-PHARMAZEUTISCHE FABRIK GMBH & CO. (DE) | 1991-08-06 | — | — | US | disclosed |
| US-5008247-A | Anticoagulants, antinflammatory agents | LUITPOLD-WERK CHEMISCH-PHARMAZEUTISCHE FABRIK GMBH & CO. (DE) | 1991-04-16 | — | — | US | disclosed |
| JP-H01143891-A | BIS-ALDONAMIDES AND PROCESS FOR THEIR PREPARATION | LUITPOLD WERK CHEM PHARMZ FAB | 1989-06-06 | — | — | JP | disclosed |
| JP-H01143890-A | POLYSULFURIC ACID ESTERS OF BIS-ALDONAMIDES AND THEIR DERIVATIVES AND PROCESS FOR THEIR PREPARATION | LUITPOLD WERK CHEM PHARMZ FAB | 1989-06-06 | — | — | JP | disclosed |
| EP-0312087-A2 | Amides of bis-aldonic acids and a method for their preparation | LUITPOLD PHARMA GmbH (DE) | 1989-04-19 | — | — | EP | disclosed |
| EP-0312086-A2 | Polysulfuric esters of amides of bis-aldonic acids and their derivatives, a method for their preparation and a drug | LUITPOLD PHARMA GmbH (DE) | 1989-04-19 | — | — | EP | disclosed |