Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 3/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL61209 | 0.84 | RET (0.47) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL59970 | 0.84 | RET (0.47) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL11604288 | 0.77 | RET (0.49) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL3656122 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL14452952 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL5529100 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL5517946 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL14452947 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL3652307 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 | |
| SCHEMBL8077348 | 0.75 | RET (0.46) | RETMAPK14CAMK1DALOX15HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491263-B1 | Phenylalkylaminoalkyl compounds; process for their preparation and pharmaceutical compositions containing same | KALI CHEMIE PHARMA GMBH (DE) | 1996-07-24 | — | — | EP | disclosed |
| EP-0491263-A1 | Phenylalkylaminoalkyl compounds; process for their preparation and pharmaceutical compositions containing same | Kali-Chemie Pharma GmbH (DE) | 1992-06-24 | — | — | EP | disclosed |