Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3652310 | 0.73 | RET (0.41) | RETMAPK14CAMK1DHDAC6 | |
| SCHEMBL7548305 | 0.72 | RET (0.33) | RETMAPK14CAMK1D | |
| Glycerin SCHEMBL27356933 | 0.68 | RET (0.37) | RETMAPK14CAMK1D | |
| SCHEMBL31089443 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 | |
| SCHEMBL3653708 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 | |
| SCHEMBL596246 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 | |
| SCHEMBL14452951 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 | |
| SCHEMBL3651148 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 | |
| SCHEMBL31509006 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 | |
| SCHEMBL3653711 | 0.67 | RET (0.53) | RETMAPK14CAMK1DHDAC6ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491263-B1 | Phenylalkylaminoalkyl compounds; process for their preparation and pharmaceutical compositions containing same | KALI CHEMIE PHARMA GMBH (DE) | 1996-07-24 | — | — | EP | disclosed |
| EP-0491243-B1 | Alkylaminoalkylamino and -ether compounds as well as processes and intermediates for their preparation, and medicaments containing these compounds | KALI CHEMIE PHARMA GMBH (DE) | 1996-05-15 | — | — | EP | disclosed |
| EP-0491243-A1 | Alkylaminoalkylamino and -ether compounds as well as processes and intermediates for their preparation, and medicaments containing these compounds | Kali-Chemie Pharma GmbH (DE) | 1992-06-24 | — | — | EP | disclosed |
| EP-0491263-A1 | Phenylalkylaminoalkyl compounds; process for their preparation and pharmaceutical compositions containing same | Kali-Chemie Pharma GmbH (DE) | 1992-06-24 | — | — | EP | disclosed |