SCHEMBL8991760

SCHEMBL8991760

CCCCCOC(C)CCCCCc1cc(S(=O)(=O)O)ccc1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 2/20 0.44
CNR2 P34972 2/20 0.37
ALDH1A1 P00352 4/20 0.37
LMNA P02545 3/20 0.37
MAPT P10636 2/20 0.37
PLA2G2C Q5R387 1/20 0.34
S1PR2 O95136 1/20 0.33
S1PR1 P21453 1/20 0.33
MAPK10 P53779 1/20 0.33
HTT P42858 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
MMP9 P14780 2/20 0.33
MMP13 P45452 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10430518 0.85 S1PR3 (0.50) S1PR3CNR2ALDH1A1LMNAMAPT
SCHEMBL7541781 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL8367731 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL8953285 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL451722 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL8578052 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL7071455 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL8764128 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL11092349 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT
SCHEMBL6677625 0.84 S1PR3 (0.47) S1PR3ALDH1A1LMNAMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5580489-A MIXING OPTICALLY ACTIVE AND INACTIVE COMPOUNDS CANON KABUSHIKI KAISHA (JP) 1996-12-03 US disclosed
US-5409636-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
EP-0352480-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-03-22 EP disclosed
US-5364559-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1994-11-15 US disclosed
EP-0347943-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-09-14 EP disclosed
EP-0355313-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-08-31 EP disclosed
US-5250217-A Improved responsiveness to electric fields CANON KABUSHIKI KAISHA (JP) 1993-10-05 US disclosed
EP-0355313-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-02-28 EP disclosed
EP-0352480-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
EP-0347943-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed