SCHEMBL8991774

SCHEMBL8991774

CCC[C@H]1CC[C@H](C(=O)OCC)CC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
ALDH1A1 P00352 5/20 0.46
PPM1B O75688 1/20 0.42
PTPN1 P18031 1/20 0.42
PPP1CC P36873 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
TSHR P16473 1/20 0.41
TAS2R14 Q9NYV8 1/20 0.41
POLB P06746 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8991772 1.00 MAPT (0.49) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL3189910 0.98 MAPT (0.47) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL3189915 0.98 MAPT (0.47) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL10479615 0.98 MAPT (0.47) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL10479620 0.98 MAPT (0.47) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL10850819 0.95 MAPT (0.45) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL9288307 0.95 MAPT (0.45) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL8215658 0.95 MAPT (0.45) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL7861017 0.90 MEN1 (0.42) MAPTMEN1KMT2AALDH1A1PPM1B
SCHEMBL7861015 0.90 MEN1 (0.42) MAPTMEN1KMT2AALDH1A1PPM1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5580489-A MIXING OPTICALLY ACTIVE AND INACTIVE COMPOUNDS CANON KABUSHIKI KAISHA (JP) 1996-12-03 US disclosed
US-5512208-A HAVING IMPROVED RESPONSIVENESS TO ELECTRIC FIELD CANON KABUSHIKI KAISHA (JP) 1996-04-30 US disclosed
US-5409636-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1995-04-25 US disclosed
EP-0352480-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-03-22 EP disclosed
EP-0350936-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-02-22 EP disclosed
EP-0350935-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1995-01-04 EP disclosed
US-5364559-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1994-11-15 US disclosed
EP-0351587-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-09-21 EP disclosed
EP-0355313-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-08-31 EP disclosed
EP-0350893-B1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KK (JP) 1994-02-02 EP disclosed
US-5250221-A Improved responsiveness to electric field CANON KABUSHIKI KAISHA (JP) 1993-10-05 US disclosed
US-5238601-A Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1993-08-24 US disclosed
US-5186858-A Mixtures of carbocyclic ethers and pyrimidine compounds having a wide driving voltage margin and able to withstand temperature fluctuations CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
EP-0355313-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-02-28 EP disclosed
EP-0352480-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-31 EP disclosed
EP-0351587-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-24 EP disclosed
EP-0350935-A1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed
EP-0350893-A1 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed
EP-0350936-A2 Ferroelectric chiral smectic liquid crystal composition and liquid crystal device using same CANON KABUSHIKI KAISHA (JP) 1990-01-17 EP disclosed