SCHEMBL8992036

SCHEMBL8992036

CO[C@H]1O[C@H](COCc2ccccc2)[C@H](O)[C@H](OCc2ccccc2)[C@H]1OCc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SSTR5 P35346 2/20 0.58
▸ SSTR1 P30872 1/20 0.58
▸ SSTR2 P30874 1/20 0.58
▸ SSTR4 P31391 1/20 0.58
▸ SSTR3 P32745 1/20 0.58
▸ PTPN1 P18031 4/20 0.49
▸ PTPN2 P17706 2/20 0.49
▸ GJB2 P29033 2/20 0.48
▸ NT5E P21589 1/20 0.48
▸ BCHE P06276 1/20 0.47
▸ SLC6A2 P23975 2/20 0.47
▸ TACR1 P25103 1/20 0.47
▸ LGALS8 O00214 1/20 0.47
▸ CDC25B P30305 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18542463 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL8336531 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL3147529 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13005449 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL4587088 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL12729388 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13088352 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL13005380 1.00 SSTR5 (0.58) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL3151671 0.96 SSTR5 (0.57) SSTR5SSTR1SSTR2SSTR4SSTR3
SCHEMBL22927969 0.94 SSTR1 (0.62) SSTR5SSTR1SSTR2SSTR4SSTR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020232194-A1 METHODS FOR GLYCOSYLATION THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2020-11-19 — — WO disclosed
US-5504078-A α-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1996-04-02 — — US disclosed
EP-0532668-B1 NOVEL ALPHA-GLUCOSIDASE INHIBITORS MERRELL DOW PHARMA (US) 1995-11-15 — — EP disclosed
EP-0345104-B1 Novel Alpha-glucosidase inhibitors MERRELL DOW PHARMA (US) 1995-11-02 — — EP disclosed
EP-0422975-B1 Alpha-glucosidase inhibitors MERRELL DOW PHARMA (US) 1994-07-27 — — EP disclosed
EP-0532668-A1 NOVEL -g(a)-GLUCOSIDASE INHIBITORS. MERRELL DOW PHARMA (US) 1993-03-24 — — EP disclosed
US-5157116-A Antidiabetic agents MERRELL DOW PHARMACEUTICALS INC. (US) 1992-10-20 — — US disclosed
US-5097023-A α-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1992-03-17 — — US disclosed
WO-1991018915-A1 NOVEL α-GLUCOSIDASE INHIBITORS MERRELL DOW PHARMACEUTICALS INC. (US) 1991-12-12 — — WO disclosed
EP-0422975-A1 Alpha-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1991-04-17 — — EP disclosed
EP-0422307-A1 Novel alpha-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1991-04-17 — — EP disclosed
EP-0389723-A1 Novel alpha-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1990-10-03 — — EP disclosed
EP-0390674-A1 Novel alpha-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1990-10-03 — — EP disclosed
EP-0345104-A2 Novel Alpha-glucosidase inhibitors MERRELL DOW PHARMACEUTICALS INC. (US) 1989-12-06 — — EP disclosed
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