Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.51 |
| ▸ | PTPRC | P08575 | 6/20 | 0.50 |
| ▸ | PTPRF | P10586 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666417 | 0.88 | KDR (0.53) | KDRCHEK1PTPN1PTPRCPTPRF | |
| SCHEMBL30174331 | 0.88 | KDR (0.53) | KDRCHEK1PTPN1PTPRCPTPRF | |
| SCHEMBL30968195 | 0.78 | KDR (0.61) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL6626948 | 0.78 | KDR (0.53) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL22541398 | 0.76 | CYP19A1 (0.48) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL8717848 | 0.75 | KDR (0.49) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL1158440 | 0.74 | KDR (0.51) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL31055001 | 0.74 | KDR (0.51) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL22541432 | 0.74 | CYP19A1 (0.48) | KDRCHEK1RAB9ANPC1KDM4E | |
| SCHEMBL5051826 | 0.73 | KDR (0.68) | KDRCHEK1RAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |